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Found 11 Enz. Inhib. hit(s) with all data for entry = 50044381
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015306(CHEMBL3263842)
Affinity DataIC50:  720nMAssay Description:Displacement of [125I]IAPP from ABCB1 (unknown origin) expressed in High Five insect cell membrane at >5 uM preincubated for 10 mins by autoradiograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015306(CHEMBL3263842)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015307(CHEMBL3263820)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human P-gpMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015308(CHEMBL3263844)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human P-gpMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015307(CHEMBL3263820)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015309(CHEMBL3263821)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015310(CHEMBL3263822)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015311(CHEMBL3263827)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015312(CHEMBL3263828)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015313(CHEMBL3263829)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human wild type P-gp expressed in BacMam virus infected human HeLa cells assessed as calcein-AM accumulation after 10 mins by flow cyto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50015306(CHEMBL3263842)
Affinity DataEC50:  27nMAssay Description:Stimulation of ATPase activity of ABCB1 (unknown origin) expressed in High Five insect cell membrane assessed as ATP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed