Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50033458
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345760(1-(Benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-i...)
Affinity DataKi:  2.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataKi:  2.56nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345758(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(piperazin...)
Affinity DataKi:  2.58nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  2.97nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345763(1-(4-Chloro benzenesulfonyl)-5-(4-methylpiperazin-...)
Affinity DataKi:  3.02nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345762(1-(3-trifluoromethyl benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  3.15nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345772(1-(4-Fluoro benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  3.21nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345753(3-Chloro-1-(2,4-difluorobenzenesulfonyl)-5-(4-meth...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345769(1-Benzenesulfonyl-5-(4-methylpiperazin-1-yl-methyl...)
Affinity DataKi:  3.83nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345756(1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-3-c...)
Affinity DataKi:  4.16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345776(1-(2,3-Dichlorobenzenesulfonyl)-5-(4-ethylpiperazi...)
Affinity DataKi:  5.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345757(3-Chloro-1-(2,4-difluoro benzenesulfonyl)-5-(piper...)
Affinity DataKi:  5.57nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345775(1-(3-trifluoromethyl benzenesulfonyl)-5-(4-ethylpi...)
Affinity DataKi:  5.72nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345774(1-(4-Isopropyl benzenesulfonyl)-5-(4-ethylpiperazi...)
Affinity DataKi:  5.81nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345761(1-(2-Bromo benzenesulfonyl)-5-(piperazin-1-yl-meth...)
Affinity DataKi:  7.77nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345765(1-(2-Bromo benzenesulfonyl)-5-(4-methylpiperazin-1...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345755(1-(4-Chlorobenzenesulfonyl)-3-chloro-5-(4-methyl p...)
Affinity DataKi:  9.33nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345773(1-(4-Methyl benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345766(1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-5-(...)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345771(1-(2,4-Difluoro benzenesulfonyl)-5-(4-ethylpiperaz...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345768(1-(4-Fluoro benzenesulfonyl)-5-(4-methylpiperazin-...)
Affinity DataKi:  14.6nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345759(1-(4-Isopropyl benzenesulfonyl)-5-(piperazin-1-yl-...)
Affinity DataKi:  14.9nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345767(1-[4-(Isopropyl benzenesulfonyl)]-5-(4-methylpiper...)
Affinity DataKi:  17.9nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345764(1-(2,3-Dichloro benzenesulfonyl)-5-(4-methylpipera...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345770(1-(4-Chloro benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  28.2nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345751(1-benzyl-5-(4-ethylpiperazin-1-yl-methyl)-1H-indol...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345752(1-Benzoyl-5-(4-methylpiperazin-1-yl-methyl)-1H-ind...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50:  1.43E+3nMAssay Description:Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human muscarinic M1 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT7 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT4 receptor expressed in CHO cells after 5 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed