Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50032951
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataIC50:  2.22E+3nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336851(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)
Affinity DataIC50:  1.99E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataIC50:  2.21E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336850(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)
Affinity DataIC50:  2.97E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)
Affinity DataIC50:  3.80E+4nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336850(3-(guanido)-1-oxo-1-hydroxy-phospholane | CHEMBL16...)
Affinity DataIC50:  5.13E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336851(3-(aminomethyl)-1-oxo-1-hydroxy-phospholane | CHEM...)
Affinity DataIC50:  5.71E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-2 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at human recombinant GABAc rho-1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50032982((3-Amino-propyl)-butyl-phosphinic acid | 3-aminopr...)
Affinity DataIC50:  5.08E+5nMAssay Description:Antagonist activity at human recombinant GABAA alpha1beta2gamma2L receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)
Affinity DataEC50:  5.00E+5nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed