Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50005384
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50257058(CHEMBL2386849)
Affinity DataIC50:  3.40nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced response by calcium mobi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50257064(CHEMBL2386850)
Affinity DataIC50:  7.80nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced response by calcium mobi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50257044(CHEMBL2386772)
Affinity DataIC50:  11nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced response by calcium mobi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50257043(CHEMBL2386771)
Affinity DataIC50:  36nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced response by calcium mobi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed