Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50043413
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440794(CHEMBL2431396)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PI3Kbeta (unknown origin) assessed as PIP2 conversion to PIP3 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440796(CHEMBL2431398)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kbeta (unknown origin) assessed as PIP2 conversion to PIP3 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440795(CHEMBL2431397)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kbeta (unknown origin) assessed as PIP2 conversion to PIP3 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440794(CHEMBL2431396)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kbeta-mediated AKT phosphorylation at Ser473 in PTEN-deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440795(CHEMBL2431397)
Affinity DataIC50: 41nMAssay Description:Inhibition of PI3Kbeta-mediated AKT phosphorylation at Ser473 in PTEN-deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50440796(CHEMBL2431398)
Affinity DataIC50: 436nMAssay Description:Inhibition of PI3Kbeta-mediated AKT phosphorylation at Ser473 in PTEN-deficient human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed