Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50043410
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50380682BDBM50380682(CHEMBL2017291 | I-BET151 (16))
Affinity DataIC50: 18nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365262BDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 24nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440727BDBM50440727(CHEMBL2431090)
Affinity DataIC50: 26nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440718BDBM50440718(CHEMBL2431078)
Affinity DataIC50: 29nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440717BDBM50440717(CHEMBL2431079)
Affinity DataIC50: 33nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440726BDBM50440726(CHEMBL2431091)
Affinity DataIC50: 36nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440716BDBM50440716(CHEMBL2431080)
Affinity DataIC50: 42nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365262BDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 69nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440715BDBM50440715(CHEMBL2431081)
Affinity DataIC50: 72nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440734BDBM50440734(CHEMBL2431082)
Affinity DataIC50: 73nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440720BDBM50440720(CHEMBL2431076)
Affinity DataIC50: 74nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440725BDBM50440725(CHEMBL2431093)
Affinity DataIC50: 86nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440717BDBM50440717(CHEMBL2431079)
Affinity DataIC50: 91nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 120nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50380682BDBM50380682(CHEMBL2017291 | I-BET151 (16))
Affinity DataIC50: 130nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440727BDBM50440727(CHEMBL2431090)
Affinity DataIC50: 140nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440716BDBM50440716(CHEMBL2431080)
Affinity DataIC50: 160nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440718BDBM50440718(CHEMBL2431078)
Affinity DataIC50: 180nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 190nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440722BDBM50440722(CHEMBL2431074)
Affinity DataIC50: 190nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440724BDBM50440724(CHEMBL2431094)
Affinity DataIC50: 190nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440723BDBM50440723(CHEMBL2431073)
Affinity DataIC50: 200nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440715BDBM50440715(CHEMBL2431081)
Affinity DataIC50: 240nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440719BDBM50440719(CHEMBL2431077)
Affinity DataIC50: 250nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440721BDBM50440721(CHEMBL2431075)
Affinity DataIC50: 250nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440728BDBM50440728(CHEMBL2431089)
Affinity DataIC50: 290nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440731BDBM50440731(CHEMBL2431085)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440726BDBM50440726(CHEMBL2431091)
Affinity DataIC50: 320nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440734BDBM50440734(CHEMBL2431082)
Affinity DataIC50: 380nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440720BDBM50440720(CHEMBL2431076)
Affinity DataIC50: 470nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440721BDBM50440721(CHEMBL2431075)
Affinity DataIC50: 710nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440730BDBM50440730(CHEMBL2431086)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440731BDBM50440731(CHEMBL2431085)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440725BDBM50440725(CHEMBL2431093)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440719BDBM50440719(CHEMBL2431077)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440722BDBM50440722(CHEMBL2431074)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440728BDBM50440728(CHEMBL2431089)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440735BDBM50440735(CHEMBL2431092)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440724BDBM50440724(CHEMBL2431094)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440733BDBM50440733(CHEMBL2431083)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440723BDBM50440723(CHEMBL2431073)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of BRD4 in human Raji cells assessed as reduction of MYC expression after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440732BDBM50440732(CHEMBL2431084)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440729BDBM50440729(CHEMBL2431087)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440736BDBM50440736(CHEMBL2431088)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of His-FLAG-tagged BRD4 binding domain1 (unknown origin) binding to H4-TetraAc-biotin peptide after 20 mins by AlphaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed