Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50044264
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010824BDBM50010824(CHEMBL3264788)
Affinity DataIC50: 24nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010823BDBM50010823(CHEMBL3264787)
Affinity DataIC50: 32nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010822BDBM50010822(CHEMBL3264786)
Affinity DataIC50: 81nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010820BDBM50010820(CHEMBL3264784)
Affinity DataIC50: 140nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010819BDBM50010819(CHEMBL3264783)
Affinity DataIC50: 140nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010835BDBM50010835(CHEMBL3264794)
Affinity DataIC50: 172nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010836BDBM50010836(CHEMBL3264795)
Affinity DataIC50: 189nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010821BDBM50010821(CHEMBL3264785)
Affinity DataIC50: 230nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010816BDBM50010816(CHEMBL3264780)
Affinity DataIC50: 320nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010815BDBM50010815(CHEMBL3264779)
Affinity DataIC50: 450nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010814BDBM50010814(CHEMBL3264778)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010722BDBM50010722(CHEMBL3264774)
Affinity DataIC50: 840nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010831BDBM50010831(CHEMBL3264792)
Affinity DataIC50: 871nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010812BDBM50010812(CHEMBL3264776)
Affinity DataIC50: 920nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010813BDBM50010813(CHEMBL3264777)
Affinity DataIC50: 930nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010811BDBM50010811(CHEMBL3264775)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010817BDBM50010817(CHEMBL3264781)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010827BDBM50010827(CHEMBL3264791)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010832BDBM50010832(CHEMBL3264793)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010681BDBM50010681(CHEMBL3264770)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010678BDBM50010678(CHEMBL3264767)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010825BDBM50010825(CHEMBL3264789)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010679BDBM50010679(CHEMBL3264768)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010823BDBM50010823(CHEMBL3264787)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 10 days by ELISA-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010823BDBM50010823(CHEMBL3264787)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 7 days by ELISA-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010682BDBM50010682(CHEMBL3264771)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010680BDBM50010680(CHEMBL3264769)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010676BDBM50010676(CHEMBL3264765)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010663BDBM50010663(CHEMBL3264752)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010683BDBM50010683(CHEMBL3264772)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010673BDBM50010673(CHEMBL3264762)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010661BDBM50010661(CHEMBL3264750)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010660BDBM50010660(CHEMBL3264749)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010818BDBM50010818(CHEMBL3264782)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010666BDBM50010666(CHEMBL3264755)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010823BDBM50010823(CHEMBL3264787)
Affinity DataIC50: 5.83E+4nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 4 days by ELISA-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010677BDBM50010677(CHEMBL3264766)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010674BDBM50010674(CHEMBL3264763)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010671BDBM50010671(CHEMBL3264760)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010672BDBM50010672(CHEMBL3264761)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010667BDBM50010667(CHEMBL3264756)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010713BDBM50010713(CHEMBL3264773)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010668BDBM50010668(CHEMBL3264757)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010826BDBM50010826(CHEMBL3264790)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010669BDBM50010669(CHEMBL3264758)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010670BDBM50010670(CHEMBL3264759)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010664BDBM50010664(CHEMBL3264753)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010665BDBM50010665(CHEMBL3264754)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010675BDBM50010675(CHEMBL3264764)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010662BDBM50010662(CHEMBL3264751)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed