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Found 7 Enz. Inhib. hit(s) with all data for entry = 50044416
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  630nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50010588((RS)-3,4-(methylenedioxy)methamphetamine | 1-(1,3-...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataKi:  8.21E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat cortex, striatum and cerebellum-dissected brain after 60 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)
Affinity DataIC50:  1.35E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50010588((RS)-3,4-(methylenedioxy)methamphetamine | 1-(1,3-...)
Affinity DataIC50:  3.04E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM85332(MDMA, R(-))
Affinity DataIC50:  1.73E+5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in Sprague-Dawley rat brain cortical membrane after 3 hrs by liquid scintillation spectrometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed