Compile Data Set for Download or QSAR
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Found 34 Enz. Inhib. hit(s) with all data for entry = 50001585
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016618(CHEMBL8370 | [(3-Nitro-benzoyl)-(4-nitro-phenyl)-a...)
Affinity DataIC50:  130nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.02 -0.64More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  230nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.07 - 1.2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016609((2-Oxo-2H-benzo[cd]indol-1-yl)-acetic acid | CHEMB...)
Affinity DataIC50:  670nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.15 - 3.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016598(CHEMBL8786 | [Benzoyl-(3-nitro-phenyl)-amino]-acet...)
Affinity DataIC50:  860nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.3 - 2.3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016604(CHEMBL267531 | [Benzoyl-(4-methoxy-phenyl)-amino]-...)
Affinity DataIC50:  960nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.1 - 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016596((Benzoyl-p-tolyl-amino)-acetic acid | CHEMBL275007)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.5 - 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016600(CHEMBL274433 | [Benzoyl-(4-chloro-phenyl)-amino]-a...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 1.5 - 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016594(CHEMBL8607 | [Acetyl-(4-nitro-phenyl)-amino]-aceti...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 0.6 - 47More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009980(CHEMBL266688 | [(Naphthalene-1-carbonyl)-phenyl-am...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 1.0 - 34More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009997((Benzoyl-phenyl-amino)-acetic acid | CHEMBL273228)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 6 - 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016621((6-Oxo-6H-phenanthridin-5-yl)-acetic acid | CHEMBL...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 4.9 - 23More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016620((Acetyl-p-tolyl-amino)-acetic acid | CHEMBL267957)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 7 - 33More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016599((Acetyl-phenyl-amino)-acetic acid | CHEMBL276168)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 5 - 97More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016601(CHEMBL274118 | [Acetyl-(4-chloro-phenyl)-amino]-ac...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 9 - 69More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016610(CHEMBL273227 | [Acetyl-(3-nitro-phenyl)-amino]-ace...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 10 - 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016608((2-Chloro-benzoylamino)-acetic acid | CHEMBL8554)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 3 - 300More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016597(CHEMBL8700 | [Acetyl-(4-hydroxy-phenyl)-amino]-ace...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 10 - 130More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009982(CHEMBL8798 | [(Naphthalene-2-carbonyl)-amino]-acet...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 25-64More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016605(CHEMBL275005 | [Acetyl-(4-amino-phenyl)-amino]-ace...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 20 - 160More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016606((2-Nitro-benzoylamino)-acetic acid | CHEMBL8681)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 32 - 110More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016602((6,11-Dioxo-6,11-dihydro-dibenzo[b,e]azepin-5-yl)-...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 8.5 - 410More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016617((4-Methoxy-benzoylamino)-acetic acid | 4-Methoxyhi...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 35-160More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016611((6-Oxo-11,12-dihydro-6H-dibenzo[b,f]azocin-5-yl)-a...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 10 - 520More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016607(CHEMBL8701 | [Acetyl-(4-methoxy-phenyl)-amino]-ace...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 7 - 130More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016622(2-[Acetyl-(4-chloro-phenyl)-amino]-propionic acid ...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 17 - 720More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016595(2-(Acetyl-p-tolyl-amino)-propionic acid | CHEMBL27...)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 16 - 360More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016612(2-(Acetyl-phenyl-amino)-propionic acid | CHEMBL417...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 10 - 1300More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016619((Benzoyl-naphthalen-2-yl-amino)-acetic acid | CHEM...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 40 - 680More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016613((4-Methyl-benzoylamino)-acetic acid | 4-Methylhipp...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 110 - 430More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016615((Benzoyl-naphthalen-1-yl-amino)-acetic acid | CHEM...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 50 - 650More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016603((4-Nitro-benzoylamino)-acetic acid | 4-Nitrohippur...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 140 - 580More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50009999(CHEMBL461 | N-benzoylglycine)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 280 - 490More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016616((4-Chloro-benzoylamino)-acetic acid | 4-Chlorohipp...)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 300 - 1100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Auburn University

Curated by ChEMBL
LigandPNGBDBM50016614(2-[Acetyl-(4-methoxy-phenyl)-amino]-propionic acid...)
Affinity DataIC50:  9.50E+5nMAssay Description:Inhibition of aldose reductase from rat lens. Value ranges from 300 - 2000More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed