Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50045241
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052244BDBM50052244(CHEMBL1652621 | US20240190872, Compound Debio-1452)
Affinity DataIC50: 29nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052239BDBM50052239(CHEMBL3322726)
Affinity DataIC50: 58nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052241BDBM50052241(CHEMBL3322728)
Affinity DataIC50: 112nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052232BDBM50052232(CHEMBL3322718)
Affinity DataIC50: 141nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052237BDBM50052237(CHEMBL3322724)
Affinity DataIC50: 161nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052227BDBM50052227(CHEMBL3322710)
Affinity DataIC50: 177nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052233BDBM50052233(CHEMBL3322720)
Affinity DataIC50: 204nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052235BDBM50052235(CHEMBL3322722)
Affinity DataIC50: 242nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052234BDBM50052234(CHEMBL3322721)
Affinity DataIC50: 242nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052223BDBM50052223(CHEMBL3322706)
Affinity DataIC50: 265nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052242BDBM50052242(CHEMBL3322729)
Affinity DataIC50: 289nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052226BDBM50052226(CHEMBL3322709)
Affinity DataIC50: 316nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052243BDBM50052243(CHEMBL3322730)
Affinity DataIC50: 316nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052230BDBM50052230(CHEMBL3322716)
Affinity DataIC50: 373nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 133673BDBM133673(US8846711, 17 | US9051321, 17)
Affinity DataIC50: 376nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052224BDBM50052224(CHEMBL3322707)
Affinity DataIC50: 378nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052240BDBM50052240(CHEMBL3322727)
Affinity DataIC50: 384nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052225BDBM50052225(CHEMBL3322708)
Affinity DataIC50: 438nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052236BDBM50052236(CHEMBL3322723)
Affinity DataIC50: 488nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052231BDBM50052231(CHEMBL3322717)
Affinity DataIC50: 709nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052238BDBM50052238(CHEMBL3322725)
Affinity DataIC50: 843nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052228BDBM50052228(CHEMBL3322712)
Affinity DataIC50: 921nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI [9-251](Staphylococcus aureus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50052229BDBM50052229(CHEMBL3322713)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of Staphylococcus aureus FabI-mediated reduction of enoyl-ACP preincubated for 30 mins measured after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed