Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50044709
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026764(CHEMBL3331509)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Ile5,6deltorphin II from delta opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]Ile5,6deltorphin II from delta opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50381677(U-69593 | CHEMBL1256748)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataIC50: 7.20nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-induced smooth muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50381677(U-69593 | CHEMBL1256748)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026764(CHEMBL3331509)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataIC50: 8.80nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum longitudinal muscle myenteric plexus assessed as inhibition of electrically-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]Ile5,6deltorphin II from delta opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataIC50: 21nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum longitudinal muscle myenteric plexus assessed as inhibition of electrically-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataIC50: 27nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-induced smooth muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataEC50:  76nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  81nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026763(CHEMBL3331511)
Affinity DataEC50:  205nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026763(CHEMBL3331511)
Affinity DataEC50:  230nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataKi:  283nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026763(CHEMBL3331511)
Affinity DataEC50:  360nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataEC50:  480nMAssay Description:Agonist activity at rat kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed