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Found 34 Enz. Inhib. hit(s) with all data for entry = 50044802
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030827(CHEMBL3355612)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030829(CHEMBL3342574)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331069((S)-6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030828(CHEMBL3355613)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030824(CHEMBL3342568)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331058(6-chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331066(6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331058(6-chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50:  61nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331059(8-chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331066(6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50:  69nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331059(8-chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331060(6,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331060(6,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030824(CHEMBL3342568)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331050(6-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331050(6-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030827(CHEMBL3355612)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331069((S)-6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331059(8-chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030824(CHEMBL3342568)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331066(6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50331060(6,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030829(CHEMBL3342574)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030828(CHEMBL3355613)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed