Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50006187
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50:  410nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(CHEMBL213805 | biphenyl-4-carboxylic acid [2-(1H-i...)
Affinity DataIC50:  6.20E+3nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(CHEMBL213302 | N-(2-(1H-indol-3-yl)ethyl)-4-chloro...)
Affinity DataIC50:  3.80E+4nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(CHEMBL209467 | N-(2-(1H-indol-3-yl)ethyl)-4-tert-b...)
Affinity DataIC50:  4.90E+4nMAssay Description:Binding affinity to human CDK4/cyclinD1 using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50: >2.50E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50: >2.50E+5nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50: >2.50E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM59087(CHEMBL258765 | Fasca-plysi | Fascaplysin)
Affinity DataIC50: >2.50E+5nMAssay Description:Binding affinity to human CDK2/cyclinEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(CHEMBL213805 | biphenyl-4-carboxylic acid [2-(1H-i...)
Affinity DataIC50: >5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(CHEMBL213302 | N-(2-(1H-indol-3-yl)ethyl)-4-chloro...)
Affinity DataIC50: >5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(CHEMBL209467 | N-(2-(1H-indol-3-yl)ethyl)-4-tert-b...)
Affinity DataIC50: >5.00E+5nMAssay Description:Binding affinity to human CDK1/cyclinB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(CHEMBL213805 | biphenyl-4-carboxylic acid [2-(1H-i...)
Affinity DataIC50:  5.21E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(CHEMBL209467 | N-(2-(1H-indol-3-yl)ethyl)-4-tert-b...)
Affinity DataIC50:  6.58E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(CHEMBL213302 | N-(2-(1H-indol-3-yl)ethyl)-4-chloro...)
Affinity DataIC50:  7.31E+5nMAssay Description:Binding affinity to human CDK2/cyclinA using GST-pRB152 as substrate by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188066(CHEMBL213302 | N-(2-(1H-indol-3-yl)ethyl)-4-chloro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188071(CHEMBL213805 | biphenyl-4-carboxylic acid [2-(1H-i...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50188064(CHEMBL209467 | N-(2-(1H-indol-3-yl)ethyl)-4-tert-b...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity to human CDK9/cyclinT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed