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Found 27 Enz. Inhib. hit(s) with all data for entry = 50044910
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50:  3.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035880(CHEMBL1437990)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035856(CHEMBL1345545)
Affinity DataIC50:  1.39E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035855(CHEMBL1505015)
Affinity DataIC50:  2.29E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035860(CHEMBL3361009)
Affinity DataIC50:  3.37E+5nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035863(CHEMBL3361012)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035864(CHEMBL3361013)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035865(CHEMBL3361014)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035866(CHEMBL3361015)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035867(CHEMBL3352903)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035869(CHEMBL3361016)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035870(CHEMBL3361017)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035871(CHEMBL3361018)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035872(CHEMBL3361019)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035873(CHEMBL3361020)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035874(CHEMBL3361021)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035875(CHEMBL3361022)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035876(CHEMBL3361023)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035877(CHEMBL3361024)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035878(CHEMBL3361025)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035879(CHEMBL3361026)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035862(CHEMBL3361011)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035861(CHEMBL3361010)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035859(CHEMBL1597544)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035858(CHEMBL3361008)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035857(CHEMBL1451460)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035868(CHEMBL579923 | GNF-Pf-4873 | SJ000233075 | TCMDC-1...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed