Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50045687
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataEC50:  2nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075200(CHEMBL3414842)
Affinity DataEC50:  15nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075198(CHEMBL3414840)
Affinity DataEC50:  32nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075196(CHEMBL3414838)
Affinity DataEC50:  58nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075202(CHEMBL3414844)
Affinity DataEC50:  59nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075195(CHEMBL3414847)
Affinity DataEC50:  60nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075197(CHEMBL3414839)
Affinity DataEC50:  63nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075198(CHEMBL3414840)
Affinity DataKd:  72nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075200(CHEMBL3414842)
Affinity DataKd:  74nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075197(CHEMBL3414839)
Affinity DataKd:  141nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075202(CHEMBL3414844)
Affinity DataKd:  151nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075196(CHEMBL3414838)
Affinity DataKd:  151nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075195(CHEMBL3414847)
Affinity DataKd:  166nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075199(CHEMBL3414841)
Affinity DataEC50:  178nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075201(CHEMBL3414843)
Affinity DataEC50:  302nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  372nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075199(CHEMBL3414841)
Affinity DataKd:  490nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075203(CHEMBL3414845)
Affinity DataEC50:  537nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataEC50:  832nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50075201(CHEMBL3414843)
Affinity DataKd:  851nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50448377(CHEMBL3121473)
Affinity DataKd:  2.14E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataKd:  2.69E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataKd:  2.69E+3nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50008072((3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5...)
Affinity DataKi:  7.94E+3nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50313638(1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-c...)
Affinity DataEC50:  8.32E+3nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataKd:  1.74E+4nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataKd:  1.74E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50313638(1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-c...)
Affinity DataKd:  5.50E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed