Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50045433
TargetKappa-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50130563((R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl...)
Affinity DataKi:  0.0300nMAssay Description:Antagonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.150nMAssay Description:Antagonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50130563((R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl...)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50000780(CHEMBL593781 | 2-(3,4-dichlorophenyl)-N-methyl-N-[...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50358171(CHEMBL1921847)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062533(CHEMBL3397594)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50130563((R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062532(CHEMBL3397593)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062536(CHEMBL3397596)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062532(CHEMBL3397593)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062533(CHEMBL3397594)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062535(CHEMBL3397595)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]U69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50130563((R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062536(CHEMBL3397596)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062535(CHEMBL3397595)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]diprenorphine from human recombinant mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062536(CHEMBL3397596)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062532(CHEMBL3397593)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062535(CHEMBL3397595)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Caen Normandie

Curated by ChEMBL
LigandPNGBDBM50062533(CHEMBL3397594)
Affinity DataKi:  254nMAssay Description:Displacement of [3H]DADLE from human recombinant delta opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2016
Entry Details Article
PubMed