Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50046176
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001922BDBM50001922(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097712BDBM50097712(CHEMBL3590203)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001922BDBM50001922(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
Affinity DataEC50:  55nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097711BDBM50097711(CHEMBL3588902)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004923BDBM50004923(CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097711BDBM50097711(CHEMBL3588902)
Affinity DataEC50:  174nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097721BDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097708BDBM50097708(CHEMBL3588903)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097722BDBM50097722(CHEMBL129399)
Affinity DataKi:  562nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421231BDBM50421231(CHEMBL2087646)
Affinity DataKi:  646nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097707BDBM50097707(CHEMBL3588904)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307216BDBM50307216(1-(3-Bromobenzyl)-1H-imidazole | CHEMBL598391)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004923BDBM50004923(CHEMBL542700 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataEC50:  1.38E+3nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106345BDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421231BDBM50421231(CHEMBL2087646)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097707BDBM50097707(CHEMBL3588904)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097719BDBM50097719(CHEMBL3588905)
Affinity DataKi:  5.25E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097718BDBM50097718(CHEMBL3588906)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097717BDBM50097717(CHEMBL3588907)
Affinity DataKi:  8.32E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097716BDBM50097716(CHEMBL3588908)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097720BDBM50097720(CHEMBL3588912)
Affinity DataKi:  1.38E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051838BDBM50051838(CHEMBL1327)
Affinity DataKi:  1.51E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097714BDBM50097714(CHEMBL3588910)
Affinity DataKi:  1.55E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097715BDBM50097715(CHEMBL3588909)
Affinity DataKi:  1.55E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097713BDBM50097713(CHEMBL3588911)
Affinity DataKi:  2.24E+4nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097713BDBM50097713(CHEMBL3588911)
Affinity DataEC50:  1.48E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051838BDBM50051838(CHEMBL1327)
Affinity DataEC50:  3.39E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097719BDBM50097719(CHEMBL3588905)
Affinity DataEC50:  4.79E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097718BDBM50097718(CHEMBL3588906)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307216BDBM50307216(1-(3-Bromobenzyl)-1H-imidazole | CHEMBL598391)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097712BDBM50097712(CHEMBL3590203)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097717BDBM50097717(CHEMBL3588907)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50106345BDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097714BDBM50097714(CHEMBL3588910)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097708BDBM50097708(CHEMBL3588903)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097716BDBM50097716(CHEMBL3588908)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50097715BDBM50097715(CHEMBL3588909)
Affinity DataEC50:  6.31E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed