Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50045778
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080870(CHEMBL3421673)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080872(CHEMBL3421675)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080871(CHEMBL3421672)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080870(CHEMBL3421673)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080873(CHEMBL3421674)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080872(CHEMBL3421675)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080871(CHEMBL3421672)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080873(CHEMBL3421674)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50346864(CHEMBL1797641 | CHEMBL3104337 | US8765820, 8)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080870(CHEMBL3421673)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50080871(CHEMBL3421672)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed