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Found 29 Enz. Inhib. hit(s) with all data for entry = 50045497
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065241(CHEMBL2207044)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065108(CHEMBL3403818)
Affinity DataIC50:  1.60E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065197(CHEMBL3403824)
Affinity DataIC50:  1.90E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065109(CHEMBL3403819)
Affinity DataIC50:  2.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065193(CHEMBL3403820)
Affinity DataIC50:  2.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065193(CHEMBL3403820)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065194(CHEMBL3403821)
Affinity DataIC50:  3.20E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065203(CHEMBL2206994)
Affinity DataIC50:  3.90E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065194(CHEMBL3403821)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065109(CHEMBL3403819)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065197(CHEMBL3403824)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065196(CHEMBL3403823)
Affinity DataIC50:  7.70E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065198(CHEMBL3403825)
Affinity DataIC50:  7.80E+3nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065199(CHEMBL3403826)
Affinity DataIC50:  1.10E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065108(CHEMBL3403818)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065203(CHEMBL2206994)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065196(CHEMBL3403823)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065199(CHEMBL3403826)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065195(CHEMBL3403822)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065195(CHEMBL3403822)
Affinity DataIC50:  1.60E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065200(CHEMBL3403827)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065200(CHEMBL3403827)
Affinity DataIC50:  1.70E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065198(CHEMBL3403825)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065202(CHEMBL3403815)
Affinity DataIC50:  2.50E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065201(CHEMBL3403816)
Affinity DataIC50:  2.50E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065202(CHEMBL3403815)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065201(CHEMBL3403816)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065236(CHEMBL3403817)
Affinity DataIC50:  5.40E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate compound preincubated for 30 mins with NADPH before substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Satori Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065236(CHEMBL3403817)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 5 mins before substrate addition by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed