Compile Data Set for Download or QSAR
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Found 33 Enz. Inhib. hit(s) with all data for entry = 50035779
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017536((Flumezapine)7-Fluoro-2-methyl-10-(4-methyl-pipera...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017524(7-Chloro-2-ethyl-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017536((Flumezapine)7-Fluoro-2-methyl-10-(4-methyl-pipera...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017521(2-Ethyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017527(7-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against dDopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017530(7-Bromo-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017523(7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Affinity DataIC50:  840nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017528(2-Methyl-10-(4-methyl-piperazin-1-yl)-7-trifluorom...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017534(6,7-Dichloro-2-methyl-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017525(7-Fluoro-1,2-dimethyl-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017523(7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017526(2-Methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017521(2-Ethyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017522(7-Fluoro-1-methyl-10-(4-methyl-piperazin-1-yl)-1,2...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017528(2-Methyl-10-(4-methyl-piperazin-1-yl)-7-trifluorom...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017526(2-Methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017534(6,7-Dichloro-2-methyl-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017524(7-Chloro-2-ethyl-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017527(7-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017530(7-Bromo-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against Muscarinic acetylcholine receptor in male olac rat brain, using [3H]-QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017529(8,9-Dichloro-5-(4-methyl-piperazin-1-yl)-11H-benzo...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017522(7-Fluoro-1-methyl-10-(4-methyl-piperazin-1-yl)-1,2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017532(3-Methyl-10-(4-methyl-piperazin-1-yl)-2,3,3a,4-tet...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017525(7-Fluoro-1,2-dimethyl-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017538(5-(4-Methyl-piperazin-1-yl)-11H-benzo[b]pyrido[2,3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf caudate tissue, using [3H]spiperone as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017535(3-Ethyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-3,4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017533(3-Cyclohexyl-7-fluoro-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017535(3-Ethyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-3,4-...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017537(7-Fluoro-3-methyl-10-(4-methyl-piperazin-1-yl)-3,4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against dopamine receptor D2 in calf caudate tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017533(3-Cyclohexyl-7-fluoro-10-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017537(7-Fluoro-3-methyl-10-(4-methyl-piperazin-1-yl)-3,4...)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibitory activity against muscarinic cholinergic receptors in male olac rat brain, using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed