Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50045573
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249090BDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)
Affinity DataKi:  96nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068779BDBM50068779(US9499493, R945071 | CHEMBL3402397 | US10828301, C...)
Affinity DataEC50:  210nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068653BDBM50068653(CHEMBL3402402)
Affinity DataEC50:  210nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068860BDBM50068860(CHEMBL3402377)
Affinity DataEC50:  230nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068858BDBM50068858(CHEMBL3402379)
Affinity DataEC50:  270nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068777BDBM50068777(CHEMBL3402399)
Affinity DataEC50:  280nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249090BDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)
Affinity DataIC50: 290nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068804BDBM50068804(CHEMBL3402388)
Affinity DataEC50:  290nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068649BDBM50068649(CHEMBL3402361 | US10828301, Compound R921302)
Affinity DataIC50: 320nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068805BDBM50068805(CHEMBL3402387)
Affinity DataEC50:  330nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249090BDBM50249090(3,3'-(5-fluoropyrimidine-2,4-diyl)bis(azanediyl)di...)
Affinity DataEC50:  350nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068856BDBM50068856(CHEMBL3402383)
Affinity DataEC50:  370nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068857BDBM50068857(CHEMBL3402380)
Affinity DataEC50:  380nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068660BDBM50068660(CHEMBL3402401)
Affinity DataEC50:  400nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068778BDBM50068778(CHEMBL3402398)
Affinity DataEC50:  430nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068855BDBM50068855(CHEMBL3402384)
Affinity DataEC50:  430nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068859BDBM50068859(CHEMBL3402378)
Affinity DataEC50:  440nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068801BDBM50068801(CHEMBL3402390)
Affinity DataEC50:  440nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068797BDBM50068797(CHEMBL3402395)
Affinity DataEC50:  450nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068649BDBM50068649(CHEMBL3402361 | US10828301, Compound R921302)
Affinity DataEC50:  460nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068800BDBM50068800(CHEMBL3402391)
Affinity DataEC50:  490nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068864BDBM50068864(CHEMBL3402373)
Affinity DataEC50:  500nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068798BDBM50068798(CHEMBL3402394)
Affinity DataEC50:  530nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068806BDBM50068806(CHEMBL3402386)
Affinity DataEC50:  670nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068799BDBM50068799(CHEMBL3402393)
Affinity DataEC50:  760nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068863BDBM50068863(CHEMBL3402374)
Affinity DataEC50:  900nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068803BDBM50068803(CHEMBL3402389)
Affinity DataEC50:  930nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068807BDBM50068807(CHEMBL3402385)
Affinity DataEC50:  940nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068869BDBM50068869(CHEMBL3402368)
Affinity DataEC50:  950nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068662BDBM50068662(CHEMBL3402400)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068650BDBM50068650(CHEMBL3402403)
Affinity DataEC50:  1.29E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31850BDBM31850(2,4-Bisanilinopyrimidine, 12)
Affinity DataEC50:  1.43E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068795BDBM50068795(CHEMBL3402396)
Affinity DataEC50:  1.55E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396072BDBM50396072(CHEMBL2170583)
Affinity DataEC50:  1.67E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068857BDBM50068857(CHEMBL3402380)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in ionomycin-induced calcium mobilization mediated degranulation by tryptase rele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068874BDBM50068874(CHEMBL3402359)
Affinity DataEC50:  1.73E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068866BDBM50068866(CHEMBL3402371)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068855BDBM50068855(CHEMBL3402384)
Affinity DataEC50:  2.48E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in ionomycin-induced calcium mobilization mediated degranulation by tryptase rele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068865BDBM50068865(CHEMBL3402372)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068861BDBM50068861(CHEMBL3402376)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068875BDBM50068875(CHEMBL3402358)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068872BDBM50068872(CHEMBL3402363)
Affinity DataEC50:  3.38E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31853BDBM31853(2,4-Bisanilinopyrimidine, 18)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068871BDBM50068871(CHEMBL3402366)
Affinity DataEC50:  4.14E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068802BDBM50068802(CHEMBL3400172)
Affinity DataEC50:  4.15E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068873BDBM50068873(CHEMBL3402360)
Affinity DataEC50:  4.25E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068868BDBM50068868(CHEMBL3402369)
Affinity DataEC50:  5.08E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068862BDBM50068862(CHEMBL3402375)
Affinity DataEC50:  5.80E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068867BDBM50068867(CHEMBL3402370)
Affinity DataEC50:  5.81E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50068870BDBM50068870(CHEMBL3402367)
Affinity DataEC50:  9.83E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
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