Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50045884
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088174(CHEMBL3427251)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088173(CHEMBL3427250)
Affinity DataIC50: 22nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088175(CHEMBL3427252)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088172(CHEMBL3427249)
Affinity DataIC50: 60nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088177(CHEMBL3427254)
Affinity DataIC50: 87nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088176(CHEMBL3427253)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088170(CHEMBL3427247)
Affinity DataIC50: 200nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088167(CHEMBL3427246)
Affinity DataIC50: 230nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50088171(CHEMBL3427248)
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 in human H4 cells stably transfected with APP751 containing Swedish mutation assessed as reduction in Abeta (1 to 40) and Abeta (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed