Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50022584
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652958BDBM50652958(CHEMBL5687004)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652960BDBM50652960(CHEMBL5687021)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652959BDBM50652959(CHEMBL5687051)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090510BDBM50090510(CHEMBL3581716)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652963BDBM50652963(CHEMBL5686988)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length mouse MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652964BDBM50652964(CHEMBL5687022)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length mouse MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652963BDBM50652963(CHEMBL5686988)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Mouse)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518060BDBM50518060(CHEMBL4455357)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length mouse MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50090617BDBM50090617(CHEMBL3581734)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652964BDBM50652964(CHEMBL5687022)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652953BDBM50652953(CHEMBL5686997)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652961BDBM50652961(CHEMBL5687019)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518060BDBM50518060(CHEMBL4455357)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652962BDBM50652962(CHEMBL5687034)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652956BDBM50652956(CHEMBL5687055)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652957BDBM50652957(CHEMBL5687024)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652954BDBM50652954(CHEMBL5687039)
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target2-acylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652955BDBM50652955(CHEMBL5687025)
Affinity DataIC50: 75nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human MGAT2 expressed in human FreeStyle 293-F cell membrane using 13Cx18oleoyl-CoA and 2-oleoyl-gly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518060BDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human DGAT1 expressed in recombinant baculovirus infected Sf21 cells using [1-14C]-oleoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518060BDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human ACAT1 expressed in recombinant baculovirus infected Sf21 cells using [1-14C]-oleoyl-CoA and ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518060BDBM50518060(CHEMBL4455357)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged full-length human DGAT2 expressed in recombinant baculovirus infected Sf21 cells using [1-14C]-oleoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed