Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50046116
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095305(CHEMBL1486348)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095306(CHEMBL3589094)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Rattus norvegicus)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Cav3.2 channel in rat DRG neurons assessed as reduction in LVA currentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of L-type calcium channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095307(CHEMBL3589546)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095308(CHEMBL3589554)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of PXR (unknown origin) assessed as induction of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of aryl hydrocarbon receptor (unknown origin) assessed as induction of CYP1A2 mRNA expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed