Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50046529
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117640BDBM50117640(CHEMBL3613639)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117639BDBM50117639(CHEMBL3613640)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117639BDBM50117639(CHEMBL3613640)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117646BDBM50117646(CHEMBL3613628)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117640BDBM50117640(CHEMBL3613639)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117638BDBM50117638(CHEMBL3613641)
Affinity DataIC50: 490nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117638BDBM50117638(CHEMBL3613641)
Affinity DataIC50: 540nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117645BDBM50117645(CHEMBL3613629)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117650BDBM50117650(CHEMBL3613638)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117652BDBM50117652(CHEMBL3613636)
Affinity DataIC50: 910nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117647BDBM50117647(CHEMBL3613627)
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117637BDBM50117637(CHEMBL3613643)
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117645BDBM50117645(CHEMBL3613629)
Affinity DataIC50: 940nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117646BDBM50117646(CHEMBL3613628)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117651BDBM50117651(CHEMBL3613637)
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117654BDBM50117654(CHEMBL3613634)
Affinity DataIC50: 1.32E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117644BDBM50117644(CHEMBL3613630)
Affinity DataIC50: 1.94E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117653BDBM50117653(CHEMBL3613635)
Affinity DataIC50: 2.11E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117644BDBM50117644(CHEMBL3613630)
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117637BDBM50117637(CHEMBL3613643)
Affinity DataIC50: 2.92E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117647BDBM50117647(CHEMBL3613627)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117641BDBM50117641(CHEMBL3613633)
Affinity DataIC50: 4.22E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117649BDBM50117649(CHEMBL3613625)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117648BDBM50117648(CHEMBL3613626)
Affinity DataIC50: 4.93E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117641BDBM50117641(CHEMBL3613633)
Affinity DataIC50: 5.74E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117648BDBM50117648(CHEMBL3613626)
Affinity DataIC50: 6.49E+3nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117649BDBM50117649(CHEMBL3613625)
Affinity DataIC50: 8.53E+3nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117642BDBM50117642(CHEMBL3613632)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117643BDBM50117643(CHEMBL3613631)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117643BDBM50117643(CHEMBL3613631)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117642BDBM50117642(CHEMBL3613632)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TRPV3 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50117636BDBM50117636(CHEMBL3613642)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in HEK293 cells assessed as inhibition of menthol-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed