Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50046541
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50:  13nMAssay Description:Inhibition of p110alpha/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  44nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  49nMAssay Description:Inhibition of p110alpha/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFKBP12A/mTOR(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50:  78nMAssay Description:Inhibition of mTORC1 (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50:  90nMAssay Description:Inhibition of p110beta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  138nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117874(CHEMBL3612310)
Affinity DataIC50:  148nMAssay Description:Inhibition of p110delta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)
Affinity DataIC50:  478nMAssay Description:Inhibition of p110beta/p85alpha (unknown origin) incubated for 40 mins by luciferase based ATP depletion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed