Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50046771
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM22032(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50090677(4-Amino-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfon...)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataIC50:  194nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130509(CHEMBL3634097)
Affinity DataIC50:  447nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130506(CHEMBL3634110)
Affinity DataIC50:  703nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50:  722nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130507(CHEMBL3634109)
Affinity DataIC50:  1.32E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130508(CHEMBL3634099)
Affinity DataIC50:  2.79E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed