Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50046677
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50:  9nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191903(US9187429, 36 | US9187429, 37 | US9187429, 38)
Affinity DataIC50:  14nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50:  21nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 5 | US9187429, 6 | US9187429, 7)
Affinity DataIC50:  25nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191908(US9187429, 43)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191899(US9187429, 30 | US9187429, 31 | US9187429, 32)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125051(CHEMBL3623821)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191876(US9187429, 1)
Affinity DataIC50:  42nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191909(US9187429, 44)
Affinity DataIC50:  47nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50:  123nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  190nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  210nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50:  530nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50:  942nMAssay Description:Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 5 | US9187429, 6 | US9187429, 7)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 5 | US9187429, 6 | US9187429, 7)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191883(US9187429, 9)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191880(US9187429, 5 | US9187429, 6 | US9187429, 7)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Pharma Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM191882(US9187429, 8)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed