Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50046780
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130865BDBM50130865(CHEMBL3634853)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130760BDBM50130760(CHEMBL3634855)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130759BDBM50130759(CHEMBL3634854)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130761BDBM50130761(CHEMBL3634856)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130763BDBM50130763(CHEMBL3634858)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130849BDBM50130849(CHEMBL3634744)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130850BDBM50130850(CHEMBL3634746)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130853BDBM50130853(CHEMBL3634748)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130860BDBM50130860(CHEMBL3634847)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130854BDBM50130854(CHEMBL3634749)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130762BDBM50130762(CHEMBL3634857)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130856BDBM50130856(CHEMBL3634751)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130858BDBM50130858(CHEMBL3634845)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Mouse)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130851BDBM50130851(CHEMBL3634747)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130840BDBM50130840(CHEMBL3634865)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of rat PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130855BDBM50130855(CHEMBL3634750)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130857BDBM50130857(CHEMBL3634752)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 6.70nMAssay Description:Binding affinity to human 5HT2bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130764BDBM50130764(CHEMBL3634859)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130859BDBM50130859(CHEMBL3634846)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130861BDBM50130861(CHEMBL3634849)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130862BDBM50130862(CHEMBL3634850)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130767BDBM50130767(CHEMBL3634862)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130769BDBM50130769(CHEMBL3634864)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130768BDBM50130768(CHEMBL3634863)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130846BDBM50130846(CHEMBL3634739)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130863BDBM50130863(CHEMBL3634851)
Affinity DataIC50: 137nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130848BDBM50130848(CHEMBL3634743)
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human 5HT2bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130847BDBM50130847(CHEMBL3634742)
Affinity DataIC50: 227nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130845BDBM50130845(CHEMBL3634735)
Affinity DataIC50: 351nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130844BDBM50130844(CHEMBL3634733)
Affinity DataIC50: 364nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130864BDBM50130864(CHEMBL3634852)
Affinity DataIC50: 926nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to dopamine receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to LTD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130841BDBM50130841(CHEMBL3634745)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to norepinephrine transporter (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130842BDBM50130842(CHEMBL3634731)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130843BDBM50130843(CHEMBL3634732)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130766BDBM50130766(CHEMBL3634861)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Glenmark Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130765BDBM50130765(CHEMBL3634860)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed