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Found 25 Enz. Inhib. hit(s) with all data for entry = 50006490
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290111(CHEMBL3747654)
Affinity DataEC50:  2.80E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289706(CHEMBL1257047)
Affinity DataEC50:  2.20E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50500248(CHEMBL3745927)
Affinity DataEC50:  400nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290142(CHEMBL3745838)
Affinity DataEC50:  700nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50500249(CHEMBL3747159)
Affinity DataEC50:  200nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290126(CHEMBL3746133)
Affinity DataEC50:  200nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290143(CHEMBL3747604)
Affinity DataEC50:  900nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290141(CHEMBL3746547)
Affinity DataEC50:  200nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290136(CHEMBL3747046)
Affinity DataEC50:  1.50E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290112(CHEMBL3746756)
Affinity DataEC50:  3.10E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289704(CHEMBL260775)
Affinity DataEC50:  1.10E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289702(CHEMBL3746059)
Affinity DataEC50:  1.40E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  400nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290136(CHEMBL3747046)
Affinity DataEC50:  1.17E+4nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290121(CHEMBL3746321)
Affinity DataEC50:  1.09E+4nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290142(CHEMBL3745838)
Affinity DataEC50:  1.90E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290127(CHEMBL3747771)
Affinity DataEC50:  300nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290120(CHEMBL3747330)
Affinity DataEC50:  3.50E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  2.80E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290122(CHEMBL3746126)
Affinity DataEC50:  300nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50500249(CHEMBL3747159)
Affinity DataEC50:  500nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290121(CHEMBL3746321)
Affinity DataEC50:  2.30E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50290119(CHEMBL3746769)
Affinity DataEC50:  400nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50289703(Lumacaftor | VRT 826809 | VRT-826809 | VX 809 | VX...)
Affinity DataEC50:  2.60E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50500248(CHEMBL3745927)
Affinity DataEC50:  200nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed