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Found 13 Enz. Inhib. hit(s) with all data for entry = 50046850
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134223(CHEMBL3742354)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human recombinant PDE10A1 expressed in baculovirus infected insect SF21 cells using [3H]cAMP as substrate after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50135189(CHEMBL3741064)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant PDE10A1 expressed in baculovirus infected insect SF21 cells using [3H]cAMP as substrate after 30 mins by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50135193(CHEMBL3741492)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE4A using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50135195(CHEMBL3741207)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE4A using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134225(CHEMBL3739783)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134220(CHEMBL3739662)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134221(CHEMBL3741850)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134222(CHEMBL3741950)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134223(CHEMBL3742354)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134224(CHEMBL3741781)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE1B using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134220(CHEMBL3739662)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE9A using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134221(CHEMBL3741850)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE9A using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Institute Of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50134222(CHEMBL3741950)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human PDE9A using [3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed