Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50006507
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50118225(ARL 69931MX | Adenosine triphosphate derivative | ...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500444(CHEMBL3747704)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500439(CHEMBL3746558)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500449(CHEMBL3746192)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500447(CHEMBL3747385)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500451(CHEMBL3746620)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500442(CHEMBL3746598)
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500443(CHEMBL3746852)
Affinity DataIC50: 360nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500443(CHEMBL3746852)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500440(CHEMBL3745863)
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500445(CHEMBL3746312)
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500445(CHEMBL3746312)
Affinity DataIC50: 1.12E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500436(CHEMBL3746901)
Affinity DataIC50: 1.35E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500438(CHEMBL3745979)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500448(CHEMBL3746177)
Affinity DataIC50: 1.97E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500447(CHEMBL3747385)
Affinity DataIC50: 2.15E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500442(CHEMBL3746598)
Affinity DataIC50: 2.24E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50118229(MRS 2179 | CHEMBL129841)
Affinity DataIC50: 2.25E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500439(CHEMBL3746558)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500436(CHEMBL3746901)
Affinity DataIC50: 2.65E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500450(CHEMBL3746188)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500450(CHEMBL3746188)
Affinity DataIC50: 4.21E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500438(CHEMBL3745979)
Affinity DataIC50: 4.90E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500449(CHEMBL3746192)
Affinity DataIC50: 5.20E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500440(CHEMBL3745863)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500441(CHEMBL3746502)
Affinity DataIC50: 7.37E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500437(CHEMBL3746451)
Affinity DataIC50: 8.80E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500441(CHEMBL3746502)
Affinity DataIC50: 9.30E+3nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500444(CHEMBL3747704)
Affinity DataIC50: 9.60E+3nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500446(CHEMBL3747288)
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500451(CHEMBL3746620)
Affinity DataIC50: 2.90E+4nMAssay Description:Antagonist activity at human platelet P2Y1 receptor assessed as inhibition of ADP-induced increase in cytosolic calcium level by FLUO-4 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500437(CHEMBL3746451)
Affinity DataIC50: 1.56E+5nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50500448(CHEMBL3746177)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human platelet P2Y12 receptor assessed as inhibition of ADP-mediated decrease in intra-platelet phosphorylated VASP by FLUO-4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50118220(adenosine(5')tetraphospho(5')adenosine | P(1),P(4)...)
Affinity DataIC50: 2.50E+5nMAssay Description:Partial antagonist activity at human platelet P2Y12 receptor assessed as inhibition of PGE1/ADP-mediated decrease in intra-platelet phosphorylated VA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed