Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50046920
TargetDihydrofolate reductase(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50138163(CHEMBL3752202)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50138163(CHEMBL3752202)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human DHFR using 45 uM DHF as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed