TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scinti...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Takeda Pharmaceuticals International
Curated by ChEMBL
Takeda Pharmaceuticals International
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescenc...More data for this Ligand-Target Pair