Compile Data Set for Download or QSAR
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Found 47 Enz. Inhib. hit(s) with all data for entry = 50046992
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.03E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  6.65E+3nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi:  6.88E+3nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  1.71E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  3.96E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142612(CHEMBL3758318)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142613(CHEMBL3758779)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142616(CHEMBL3759154)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142611(CHEMBL3759856)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142610(CHEMBL3759124)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142609(CHEMBL3759138)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142608(CHEMBL3759809)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142607(CHEMBL3759390)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142606(CHEMBL3758252)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142605(CHEMBL3759527)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142604(CHEMBL3759334)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142603(CHEMBL3759469)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.23E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  5.41E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  5.47E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  5.51E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  7.81E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  8.40E+4nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)
Affinity DataKi:  9.23E+4nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  1.05E+5nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  1.36E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)
Affinity DataIC50:  3.70E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataIC50:  6.30E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50192229(3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...)
Affinity DataEC50:  7.60E+3nMAssay Description:Agonist activity at human GluA2(Q)i expressed in HEK293 cells assessed as enhancement of glutamate-evoked desensitized current by whole cell patch cl...More data for this Ligand-Target Pair