Found 86 Enz. Inhib. hit(s) with all data for entry = 50046861 TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 115nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 759nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 186nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 617nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 759nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 148nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 105nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 302nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 692nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 7.94E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 91nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: <3.02E+4nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 7.76E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.82E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.23E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: <3.02E+4nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 620nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 760nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataEC50: 690nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
