Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50047138
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150477(CHEMBL3769686)
Affinity DataIC50:  20nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150519(CHEMBL3769487)
Affinity DataIC50:  29nMAssay Description:Modulation of gamma secretase in human H4 cells transfected with APP751 SWE clone 8.20 mutant assessed as inhibition of amyloid beta (1 to 42) produc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150515(CHEMBL3771295)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150473(CHEMBL3769671)
Affinity DataIC50:  35nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150507(CHEMBL3771055)
Affinity DataIC50:  40nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150512(CHEMBL3769926)
Affinity DataIC50:  50nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150479(CHEMBL3769539)
Affinity DataIC50:  50nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150480(CHEMBL3771303)
Affinity DataIC50:  80nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150516(CHEMBL3770105)
Affinity DataIC50:  100nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150481(CHEMBL3771153)
Affinity DataIC50:  120nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150475(CHEMBL3769916)
Affinity DataIC50:  140nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150474(CHEMBL3770756)
Affinity DataIC50:  140nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150512(CHEMBL3769926)
Affinity DataIC50:  150nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150503(CHEMBL3770314)
Affinity DataIC50:  180nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150518(CHEMBL3769431)
Affinity DataIC50:  180nMAssay Description:Modulation of gamma secretase in human H4 cells transfected with APP751 SWE clone 8.20 mutant assessed as inhibition of amyloid beta (1 to 42) produc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150513(CHEMBL3770111)
Affinity DataIC50:  190nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150516(CHEMBL3770105)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150517(CHEMBL3770272)
Affinity DataIC50:  200nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150509(CHEMBL3769523)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150508(CHEMBL3769445)
Affinity DataIC50:  300nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150511(CHEMBL3770902)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150510(CHEMBL3769470)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150508(CHEMBL3769445)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150507(CHEMBL3771055)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150503(CHEMBL3770314)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150510(CHEMBL3769470)
Affinity DataIC50:  380nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150514(CHEMBL3771031)
Affinity DataIC50:  460nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150473(CHEMBL3769671)
Affinity DataIC50:  700nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150515(CHEMBL3771295)
Affinity DataIC50:  820nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150511(CHEMBL3770902)
Affinity DataIC50:  1.00E+3nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150509(CHEMBL3769523)
Affinity DataIC50:  1.10E+3nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150476(CHEMBL3771224)
Affinity DataIC50:  1.20E+3nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150478(CHEMBL3771297)
Affinity DataIC50:  1.80E+3nMAssay Description:Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150514(CHEMBL3771031)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150517(CHEMBL3770272)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50150513(CHEMBL3770111)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed