Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 7320
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189355(4-(4-Methylpiperazin-1-yl)-6-(pyridin-4-yl)-1,3,5-...)
Affinity DataKi:  3.19E+3nM ΔG°:  -29.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189346(N-(4-Chlorophenyl)-4-methylpiperazine-1-carboxamid...)
Affinity DataKi:  3.52E+3nM ΔG°:  -28.9kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189344((3-Chlorophenyl)(4-methylpiperazin-1-yl)methanone ...)
Affinity DataKi:  3.88E+3nM ΔG°:  -28.7kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189352(4-(4-Methylpiperazin-1-yl)-6-(naphthalen-1-ylmethy...)
Affinity DataKi:  5.60E+3nM ΔG°:  -27.9kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189353(4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-...)
Affinity DataKi:  7.50E+3nM ΔG°:  -27.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189345((4-Chlorophenyl)(4-methylpiperazin-1-yl)methanone ...)
Affinity DataKi:  7.55E+3nM ΔG°:  -27.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189351(4-(4-Methylpiperazin-1-yl)-6-(2-methylpropyl)-1,3,...)
Affinity DataKi:  8.26E+3nM ΔG°:  -27.0kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189354(4-((4-Chlorophenoxy)methyl)-6-(4-methylpiperazin-1...)
Affinity DataKi:  1.06E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189350(3-((4-Amino-6-(4-methylpiperazin-1-yl)-1,3,5-triaz...)
Affinity DataKi:  1.46E+4nM ΔG°:  -25.7kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189348(3,6-Dichloro-N-(3-(4-methylpiperazin-1-yl)propyl)b...)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189347(5-Chloro-N-(3-(4-methylpiperazin-1-yl)propyl)-1H-i...)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189343((2-Chlorophenyl)(4-methylpiperazin-1-yl)methanone ...)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College

LigandPNGBDBM189349(1-(3-Chlorophenyl)-3-(3-(4-methylpiperazin-1-yl)pr...)
Affinity DataKi: >1.00E+5nM ΔG°: >-21.2kJ/molepH: 7.4 T: 2°CAssay Description:Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed