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Found 40 Enz. Inhib. hit(s) with all data for entry = 50047408
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165571(CHEMBL3800471)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165466(CHEMBL3800420)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of c-Met in human MKN45 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165567(CHEMBL3797914)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165578(CHEMBL3799192)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165467(CHEMBL3798905)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165466(CHEMBL3800420)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165572(CHEMBL3800559)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165468(CHEMBL3799263)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165468(CHEMBL3799263)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  0.950nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165565(CHEMBL3800295)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165576(CHEMBL3800427)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165470(CHEMBL3797871)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165575(CHEMBL3798623)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165570(CHEMBL3798174)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165467(CHEMBL3798905)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165569(CHEMBL3797547)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165574(CHEMBL3797307)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165476(CHEMBL3800061)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165568(CHEMBL3798660)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165566(CHEMBL3799924)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165573(CHEMBL3798130)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165564(CHEMBL3798590)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  5.5nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165577(CHEMBL3798542)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor/Nucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  8.60nMAssay Description:Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM163243(US9062045, Comparator No. 1 (JNJ-38877605))
Affinity DataIC50:  9.5nMAssay Description:Inhibition of c-Met in human MKN45 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165503(CHEMBL3798746)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  80nMAssay Description:Inhibition of TPR-MET in mouse NIH/3T3 cells assessed as inhibition of cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165500(CHEMBL3798974)
Affinity DataIC50:  127nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165501(CHEMBL3799231)
Affinity DataIC50:  129nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165502(CHEMBL3798619)
Affinity DataIC50:  413nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant c-Mer (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant TYRO3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165465(CHEMBL3797579)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant AXL (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed