Found 20 Enz. Inhib. hit(s) with all data for entry = 50047536 
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]A-804598 from human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]A-804598 from rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]A-804598 from human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]A-804598 from rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]A-804598 from human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Displacement of [3H]A-804598 from rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Displacement of [3H]A-804598 from human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 489nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Antagonist activity against ATP-gated P2X7 receptor in LPS-stimulated human whole blood assessed as reduction in P2X7 agonist 2'(3')-O-(4-benzoylbenz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Antagonist activity against ATP-gated P2X7 receptor in LPS-stimulated human whole blood assessed as reduction in P2X7 agonist 2'(3')-O-(4-benzoylbenz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 1.46E+3nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity against ATP-gated P2X7 receptor in LPS-stimulated human whole blood assessed as reduction in P2X7 agonist 2'(3')-O-(4-benzoylbenz...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 5.97E+3nMAssay Description:Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...More data for this Ligand-Target Pair
