Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50047376
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163507(CHEMBL3794256)
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163509(CHEMBL3578244)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163507(CHEMBL3794256)
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163507(CHEMBL3794256)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ mobilization measured every 2 secs by fluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163508(CHEMBL3578243)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163497(CHEMBL3578242)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163497(CHEMBL3578242)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163509(CHEMBL3578244)
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163500(CHEMBL3793841)
Affinity DataIC50: 38nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163508(CHEMBL3578243)
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163505(CHEMBL3793016)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163553(CHEMBL3792826)
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163501(CHEMBL3793001)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163500(CHEMBL3793841)
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163504(CHEMBL3792764)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163502(CHEMBL3793312)
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163509(CHEMBL3578244)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ mobilization measured every 2 secs by fluorom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163499(CHEMBL3792893)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163501(CHEMBL3793001)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163510(CHEMBL3794501)
Affinity DataIC50: 99nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163504(CHEMBL3792764)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163506(CHEMBL3794208)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163502(CHEMBL3793312)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163503(CHEMBL3793142)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]-MCH(4 to 19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163505(CHEMBL3793016)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163554(CHEMBL3793053)
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163499(CHEMBL3792893)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163506(CHEMBL3794208)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163503(CHEMBL3793142)
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163509(CHEMBL3578244)
Affinity DataIC50: 1.00E+4nMAssay Description:Time-dependent inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163509(CHEMBL3578244)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed