Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 50047842
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataKi:  5.30E+3nMAssay Description:Competitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent peptide substrate in presence of NAD+ by Lineweaver-Burk p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataKi:  9.80E+3nMAssay Description:Noncompetitive inhibition of human SIRT2 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by Lineweaver-Burk plot a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193080(CHEMBL3951539)
Affinity DataIC50:  93nMAssay Description:Inhibition of full-length human N-terminal GST-tagged SIRT1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50438910(CHEMBL1450796 | US9073941, 618)
Affinity DataIC50:  110nMAssay Description:Inhibition of human SIRT1 using biotinylated peptide with an acetylated FLAG sequence as substrate measured after 3 hr in presence of NAD+ by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193045(CHEMBL3986181)
Affinity DataIC50:  110nMAssay Description:Inhibition of human SIRT1 using biotinylated peptide with an acetylated FLAG sequence as substrate measured after 3 hr in presence of NAD+ by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193074(CHEMBL3933232)
Affinity DataIC50:  149nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50:  297nMAssay Description:Inhibition of full-length human N-terminal GST-tagged SIRT1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human SIRT1 using biotinylated peptide with an acetylated FLAG sequence as substrate measured after 3 hr in presence of NAD+ by TR-FRET...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193076(CHEMBL3900138)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of recombinant human SIRT1 (193 to 747 residues) expressed in Escherichia coli BL21 (DE3) using AMC-labeled p53-derived acetylated lysine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193073(CHEMBL2397737)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of full-length human N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50178767(2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | CH...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193080(CHEMBL3951539)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of full-length human N-terminal His6-tagged SIRT2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of deacetylase activity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50215507(6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193075(CHEMBL3902988)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193081(CHEMBL271761)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human FLAG-tagged SIRT1 expressed in HEK293 cells using [3H]-H3 peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193043(CHEMBL3920465)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant human SIRT1 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor de Lys ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193078(CHEMBL3956664)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of recombinant human SIRT2 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human N-terminal 6His-tagged SIRT2 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50190132(CHEMBL3828225)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM99917(4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)ph...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human SIRT2 assessed as deacetylation activity using acetylated lysine as substrate measured after 1 hr in presence of NAD+ by by Fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of human SIRT2 using biotin labeled histone H4 peptide with an acetylated lysine 4 as substrate measured after 1 hr by luminescence analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50178772(6-hydroxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193056(CHEMBL3980009)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human SIRT1 assessed as deacetylation activity preincubated with protein followed by addition of AMC-tagged Arg-His-Lys-Lys(Ac) (379 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50297159(2-(phenylamino)benzamide | CHEMBL561194)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193043(CHEMBL3920465)
Affinity DataIC50: <2.03E+4nMAssay Description:Inhibition of human N-terminal 6His-tagged SIRT2 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM99917(4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)ph...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human SIRT1 assessed as deacetylation activity using acetylated lysine as substrate measured after 1 hr in presence of NAD+ by by Fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193078(CHEMBL3956664)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50190132(CHEMBL3828225)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193044(CHEMBL3942319)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human SIRT1 assessed as deacetylation activity preincubated with protein followed by addition of AMC-tagged Arg-His-Lys-Lys(Ac) (379 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193046(CHEMBL3969626)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant human SIRT1 assessed as deacetylation activity using fluorescent substrate in presence of NAD+ by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human GST-tagged SIRT1 (18 to 340 residues) expressed in Escherichia coli BL21 (DE3)LysS using acetylated HeLa histones as substrate me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50396052(CHEMBL2170195)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human SIRT1 assessed as NAD+-dependent deacetylase activity using acetylated tubuline as substrate measured after overnight incubation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50: <5.00E+4nMAssay Description:Non-competitive inhibition of recombinant human SIRT1 using acetylated histone as substrate measured after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50: <5.00E+4nMAssay Description:Non-competitive inhibition of recombinant yeast glutathione-S-transferase-tagged SIRT2 using acetylated histone as substrate measured after 30 mins b...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of recombinant human SIRT1 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor de Lys ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human SIRT1 expressed in bacterial expression system assessed as reduction in conversion of [3H]acetyl-H4 to [3H]acetic acid measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of human GST-tagged SIRT2 expressed in bacterial expression system assessed as deacetylation activity using [3H]acetyl-H4 peptide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent histone deacetylase SIR2(Saccharomyces cerevisiae)
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant yeast Sir2p using acetylated HeLa histones as substrate measured after 2 hrs in presence of NAD by scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50297159(2-(phenylamino)benzamide | CHEMBL561194)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of SIRT2 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50392085(CHEMBL2152587)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50309827(CHEMBL597845 | Salermide)
Affinity DataIC50:  7.62E+4nMAssay Description:Inhibition of recombinant human His-tagged SIRT1 assessed as inhibition of deacetylase activity measured after 60 mins by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50392084(CHEMBL2152586 | US9284299, PNU-74654)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50438910(CHEMBL1450796 | US9073941, 618)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT2 using biotin labeled histone H4 peptide with an acetylated lysine 4 as substrate measured after 1 hr by luminescence analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193045(CHEMBL3986181)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human SIRT2 using biotin labeled histone H4 peptide with an acetylated lysine 4 as substrate measured after 1 hr by luminescence analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193047(CHEMBL3915417)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SIRT1 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50297159(2-(phenylamino)benzamide | CHEMBL561194)
Affinity DataIC50:  2.35E+5nMAssay Description:Inhibition of SIRT3 (unknown origin) using acetylated lysine as substrate by Fluor de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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