Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50012537
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50228080(Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558138(CHEMBL4792628)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558141(CHEMBL4759836)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558133(CHEMBL4764165)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558153(CHEMBL4798697)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558143(CHEMBL4794194)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558139(CHEMBL4777170)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558135(CHEMBL4776613)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558136(CHEMBL4563704)
Affinity DataIC50: 115nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558144(CHEMBL4790021)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558148(CHEMBL4746794)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | SC-66110 | EPLERENONE)
Affinity DataIC50: 244nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558142(CHEMBL4755269)
Affinity DataIC50: 275nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558148(CHEMBL4746794)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558137(CHEMBL4749536)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558137(CHEMBL4749536)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558154(CHEMBL4742925)
Affinity DataIC50: 530nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558149(CHEMBL4754975)
Affinity DataIC50: 940nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558134(CHEMBL4796191)
Affinity DataIC50: 960nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558152(CHEMBL4747722)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558157(CHEMBL4748904)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558132(CHEMBL4792176)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558152(CHEMBL4747722)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558140(CHEMBL4760159)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558145(CHEMBL4759690)
Affinity DataIC50: 2.12E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558150(CHEMBL4756852)
Affinity DataIC50: 2.31E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558151(CHEMBL4777887)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558136(CHEMBL4563704)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558154(CHEMBL4742925)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558138(CHEMBL4792628)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558158(CHEMBL4746832)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558147(CHEMBL4798873)
Affinity DataIC50: 4.80E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558153(CHEMBL4798697)
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558146(CHEMBL4763926)
Affinity DataIC50: 7.90E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558155(CHEMBL4794041)
Affinity DataIC50: 9.80E+3nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50558156(CHEMBL4780739)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human full-length MCR assessed as inhibition of receptor binding to co-activator peptide by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck And

Curated by ChEMBL
LigandPNGBDBM50510665(CHEMBL4439903)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed