Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50047684
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183021BDBM50183021(CHEMBL3818646)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183022BDBM50183022(CHEMBL3819019)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataKi:  0.770nMAssay Description:Competitive inhibition of TTK (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183023BDBM50183023(CHEMBL3819328)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081539BDBM50081539(CHEMBL3422104)
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged TTK using biotinylated PWDPDDADITEILG as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183036BDBM50183036(CHEMBL3818403)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183041BDBM50183041(CHEMBL3819003)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183025BDBM50183025(CHEMBL3818533)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183027BDBM50183027(CHEMBL3817905)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183024BDBM50183024(CHEMBL3819182)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged TTK using biotinylated PWDPDDADITEILG as substrate preincubated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183035BDBM50183035(CHEMBL3818766)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183020BDBM50183020(CHEMBL3819637)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183034BDBM50183034(CHEMBL3819164)
Affinity DataIC50: 7nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183038BDBM50183038(CHEMBL3817949)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183026BDBM50183026(CHEMBL3818733)
Affinity DataIC50: 9nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183033BDBM50183033(CHEMBL3818914)
Affinity DataIC50: 10nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183037BDBM50183037(CHEMBL3819318)
Affinity DataIC50: 11nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183039BDBM50183039(CHEMBL3819612)
Affinity DataIC50: 14nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183028BDBM50183028(CHEMBL3817922)
Affinity DataIC50: 15nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183040BDBM50183040(CHEMBL3817849)
Affinity DataIC50: 24nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183029BDBM50183029(CHEMBL3818025)
Affinity DataIC50: 32nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183031BDBM50183031(CHEMBL3818485)
Affinity DataIC50: 230nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183022BDBM50183022(CHEMBL3819019)
Affinity DataIC50: 470nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183030BDBM50183030(CHEMBL3818271)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183032BDBM50183032(CHEMBL3819411)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183023BDBM50183023(CHEMBL3819328)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183020BDBM50183020(CHEMBL3819637)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183021BDBM50183021(CHEMBL3818646)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human His-tagged Aurora B/full length recombinant human N-terminal GST-tagged INCENP (821-end residues) expressed in baculo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged Aurora A expressed in Sf21 cells by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183019BDBM50183019(CHEMBL3819210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PLK4 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed