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Found 11 Enz. Inhib. hit(s) with all data for entry = 50047895
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196073(CHEMBL3919081)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196066(20-O-Acetylneoavarol | CHEMBL516014)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196071(CHEMBL3971802)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196070(CHEMBL3962935)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196064(CHEMBL521017)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196067(CHEMBL3893783)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196068(CHEMBL3892140)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242257(2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196065(CHEMBL3973897)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196072(3''-Amino-Avarone | CHEMBL464646)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed