Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50009842
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi:  200nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi:  200nMAssay Description:Inhibition of human alpha-thrombin using S-2366 as substrate after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532740(CHEMBL4518749)
Affinity DataKi: >5.40E+3nMAssay Description:Inhibition of human trypsin 1 using S-2222 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.70E+4nMAssay Description:Inhibition of human F10a using S-2765 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human plasmin using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >1.90E+4nMAssay Description:Inhibition of human F11a using S-2366 as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataKi: >2.90E+4nMAssay Description:Inhibition of human F9a using pefachrome F9a as substrate preincubated for 300 secs followed by substrate addition measured after 40 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532742(CHEMBL4455063)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50532741(CHEMBL4443619)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed