Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50048148
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432578BDBM50432578(CHEMBL2347165)
Affinity DataIC50: 13nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432578BDBM50432578(CHEMBL2347165)
Affinity DataKi:  50nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206364BDBM50206364(CHEMBL3933129)
Affinity DataIC50: 54nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206365BDBM50206365(CHEMBL3929246)
Affinity DataIC50: 85nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206360BDBM50206360(CHEMBL3960919)
Affinity DataIC50: 270nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206372BDBM50206372(CHEMBL3920217)
Affinity DataIC50: 350nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206367BDBM50206367(CHEMBL3892909)
Affinity DataIC50: 360nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206380BDBM50206380(CHEMBL3899797)
Affinity DataIC50: 370nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206374BDBM50206374(CHEMBL3910108)
Affinity DataIC50: 370nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206366BDBM50206366(CHEMBL3980103)
Affinity DataIC50: 490nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396414BDBM50396414(CHEMBL1370773)
Affinity DataIC50: 500nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206368BDBM50206368(CHEMBL3919858)
Affinity DataIC50: 650nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206373BDBM50206373(CHEMBL3890813)
Affinity DataIC50: 660nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206379BDBM50206379(CHEMBL3980225)
Affinity DataIC50: 670nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206369BDBM50206369(CHEMBL3925807)
Affinity DataIC50: 700nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206381BDBM50206381(CHEMBL3981926)
Affinity DataIC50: 700nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206364BDBM50206364(CHEMBL3933129)
Affinity DataKi:  800nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206362BDBM50206362(CHEMBL3972038)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206361BDBM50206361(CHEMBL3953437)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206375BDBM50206375(CHEMBL3956919)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206383BDBM50206383(CHEMBL3947640)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206378BDBM50206378(CHEMBL3938850)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206382BDBM50206382(CHEMBL3901888)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206371BDBM50206371(CHEMBL3943673)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125096BDBM50125096(CHEMBL162522 | 1,4-Dibenzyl-piperazine, 9 | 1,4-Di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206370BDBM50206370(CHEMBL3938741)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206376BDBM50206376(CHEMBL3932693)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206363BDBM50206363(CHEMBL3138959)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206377BDBM50206377(CHEMBL3904692)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206372BDBM50206372(CHEMBL3920217)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Free University of Brussels

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206360BDBM50206360(CHEMBL3960919)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed