Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50001845
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018459(1-(7-Methoxy-naphthalen-1-yl)-piperazine | 4-(7-Me...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018456(2-{5-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-pentyl}...)
Affinity DataKi:  5nMAssay Description:Binding affinity of compound towards 5-HT 1A receptor by measuring ability to displace [3H]-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat stria...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018452(2-[5-(4-Phenyl-piperazin-1-yl)-pentyl]-isoindole-1...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018458(2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-isoindole-1,...)
Affinity DataKi:  10nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM30707(2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...)
Affinity DataKi:  10nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018449(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-isoindole-1,...)
Affinity DataKi:  11nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018457(2-{4-[2-(5-Methoxy-1H-indol-3-yl)-ethylamino]-buty...)
Affinity DataKi:  20nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018451(2-{4-[3-(Naphthalen-1-yloxy)-propylamino]-butyl}-i...)
Affinity DataKi:  25nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018463(1-(2-Methoxy-naphthalen-1-yl)-piperazine | CHEMBL2...)
Affinity DataKi:  34nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018468(2-{3-[3-(Naphthalen-1-yloxy)-propylamino]-propyl}-...)
Affinity DataKi:  45nMAssay Description:Binding affinity of compound towards 5-HT 1A receptor by measuring ability to displace [3H]-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat stria...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018454(2-[3-(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataKi:  48nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018466(2-[4-(3-Phenyl-propylamino)-butyl]-isoindole-1,3-d...)
Affinity DataKi:  65nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018462(2-{4-[3-(2-Methoxy-phenyl)-propylamino]-butyl}-iso...)
Affinity DataKi:  110nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018461(2-(4-{[3-(2-Methoxy-phenyl)-propyl]-methyl-amino}-...)
Affinity DataKi:  170nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018464(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-isoindole-1...)
Affinity DataKi:  200nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018460(2-(4-Phenethylamino-butyl)-isoindole-1,3-dione | C...)
Affinity DataKi:  240nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018450(2-[2-(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl...)
Affinity DataKi:  250nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018455(2-[4-(Methyl-phenethyl-amino)-butyl]-isoindole-1,3...)
Affinity DataKi:  300nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018453(CHEMBL46278 | Dimethyl-phenethyl-amine | N,N-dimet...)
Affinity DataKi:  850nMAssay Description:Binding affinity of compound towards 5-HT 1A receptor by measuring ability to displace [3H]-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat stria...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018467(2-{2-[3-(Naphthalen-1-yloxy)-propylamino]-ethyl}-i...)
Affinity DataKi:  1.33E+3nMAssay Description:Binding affinity of compound towards 5-HT 1A receptor by measuring ability to displace [3H]-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat stria...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018465(CHEMBL27279 | [3-(2-Methoxy-phenyl)-propyl]-dimeth...)
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018449(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-isoindole-1,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed