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Found 20 Enz. Inhib. hit(s) with all data for entry = 50010091
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535062(CHEMBL4563498)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535066(CHEMBL4461324)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535064(CHEMBL4588254)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535064(CHEMBL4588254)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535068(CHEMBL4471266)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535061(CHEMBL4538175)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535060(CHEMBL4461039)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535063(CHEMBL4559331)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535065(CHEMBL4528204)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535062(CHEMBL4563498)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535060(CHEMBL4461039)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535063(CHEMBL4559331)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535068(CHEMBL4471266)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535067(CHEMBL4468689)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535065(CHEMBL4528204)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535061(CHEMBL4538175)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535066(CHEMBL4461324)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human COX2 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
American University Of Madaba

Curated by ChEMBL
LigandPNGBDBM50535067(CHEMBL4468689)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of ovine COX1 assessed as PGH2 formation preincubated for 10 mins followed by addition of arachidonic acid as substrate measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed