Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50047887
LigandPNGBDBM32628(Fumitremorgin C | FTC)
Affinity DataIC50: 960nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195540(CHEMBL3898212)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195542(CHEMBL3895919)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195541(CHEMBL3984719)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195539(CHEMBL3926291)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195544(CHEMBL3891465)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandPNGBDBM50195545(CHEMBL3923932)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195541(CHEMBL3984719)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195545(CHEMBL3923932)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195543(CHEMBL2236206)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195542(CHEMBL3895919)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195540(CHEMBL3898212)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195539(CHEMBL3926291)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University Bayreuth

Curated by ChEMBL
LigandPNGBDBM50195544(CHEMBL3891465)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed